SmartFTP is an excellent, free for personal use FTP client. Not only that, but for £20 ($36), it well worth the purchase too. Whats new:

• New GUI (Tabbed Windows, Docking Panes, Full Customization)
• Workspace Manager
• Auto Layout for Windows
• New Local Browser
• New Remote Browser
• Automatic Backup of Settings and Data
• Requirements: Windows 98/ME (Limited Support), Windows 2000, Windows XP, Windows 2003, Windows Vista
• Native 64bit version for Windows x64 Editions